mouse lung tissue were subjected to SDS PAGE followed by western blot with FNab02761(ENG antibody) at dilution of 1:300
IP Result of anti- CD105 (IP: FNab02761, 3ug; Detection: FNab02761 1:300) with mouse lung tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded human pancreas using FNab02761(ENG antibody) at dilution of 1:4000
Background
This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.